What sexual health concerns does RFC Longevity treat?

Low libido. Vaginal dryness and atrophy. Painful intercourse (dyspareunia). Loss of arousal. Difficulty with orgasm. Post-childbirth tissue changes. Post-menopausal sexual function decline. Reduced sensation. We address these through hormone optimization, regenerative therapies (Vaginal PRP, low-level laser therapy, ozone), microbiome restoration, and individualized clinical protocols. Sexual wellness isn't a bolt-on aesthetic service at RFC — it's measured and treated as a core longevity outcome. Dr. Merhi is one of the few reproductive endocrinologists in the U.S. integrating these therapies into a longevity framework.

Why is sexual wellness part of a longevity program?

Because sexual function is one of the most reliable indicators of how a woman's body is aging — and most longevity programs ignore it entirely. Libido depends on testosterone, estradiol, DHEA, and dopamine signaling. Vaginal tissue health reflects estrogen status, microbiome integrity, and inflammatory burden. Orgasmic function tracks pelvic blood flow and nerve health. We measure all of it because it tells us things blood pressure and ApoB don't. Sexual wellness isn't separate from longevity — it's longevity, in one of its most measurable forms.

Is Vaginal PRP safe? What does the procedure involve?

Vaginal PRP uses a small sample of your own blood, processed to concentrate the growth factors and platelets, then injected into vaginal and surrounding tissue to stimulate regeneration. Because the material is your own blood, there's no risk of allergic reaction or rejection. The procedure takes under an hour, is performed in-office with local anesthetic, and most patients return to normal activity within 24–48 hours. It's part of the same regenerative platform RFC pioneered for ovarian rejuvenation.

Is RFC Longevity covered by insurance?

No. RFC Longevity is a private, application-based program. Insurance does not cover preventive longevity care, advanced biomarker panels, or regenerative therapies in the United States. Some specific lab work and prescriptions ordered through the program may be reimbursable through your existing insurance — we provide superbills you can submit. But the program fees themselves are paid out of pocket, like any concierge medical program.

Do I need to live in NYC or Connecticut?

Most patients travel in for the testing visit and physician review, then continue on telehealth from anywhere in the U.S. We have five physical locations across Manhattan, Brooklyn, Westchester, Long Island, and Westport, CT — plus an option for in-person treatment retreats in the Bahamas for select patients in our Deep Dive pathway. Roughly half of our patients fly in once a year for testing and stay local; the other half live in the tri-state area.

How is RFC Longevity different from Function Health?

Function Health is an algorithm-driven biomarker dashboard with optional generalist physician review. RFC Longevity is a physician-built clinical program where Dr. Merhi — a reproductive endocrinologist with 110+ peer-reviewed publications — personally reviews every panel and builds every protocol. Function Health is a self-serve tool. RFC Longevity is medicine. The other major difference: Function Health doesn't address sexual wellness, regenerative therapies, or reproductive health at any meaningful clinical level. We do.

How is RFC Longevity different from Atria, Fountain Life, or other concierge longevity clinics?

Most concierge longevity programs were designed by general internists who added hormone testing as an afterthought. RFC Longevity is the inverse — built outward from a reproductive endocrinology foundation. That means we read hormones, fertility markers, sexual function, microbiome, and metabolic signals as one connected system. Other programs price at $20K–$100K per year. We're priced from $2K to $10K. The depth, especially around female-specific biology, is what's different.

Does RFC Longevity treat men?

Not currently. RFC Longevity is designed specifically around female reproductive, sexual, and hormonal biology — and the medicine, biomarkers, and therapies are calibrated for women. The longevity industry already has many programs built around male physiology; we built this one for the half of the population that's been treated as a footnote.

What does “personalized protocol” actually mean? Is this just a generic supplement stack?

No. After your testing and physician review, Dr. Merhi builds a written, individualized plan that connects every finding in your panel to a specific therapy or intervention. That can include prescription hormone optimization, IV nutrient protocols, regenerative procedures (where appropriate), microbiome restoration, targeted supplementation, and lifestyle adjustments. The protocol is calibrated to your biomarker pattern. There is no template. Two women in the same age bracket with the same symptoms will often leave with different protocols because their underlying drivers are different.

I'm already in perimenopause or menopause. Is it too late?

It's not too late. Perimenopause and menopause are exactly the windows where most women in the U.S. fall through the cracks of standard care — and where the right interventions create the most measurable change. Hormone optimization, sexual wellness restoration (including Vaginal PRP and LLLT for vaginal tissue regeneration), bone health monitoring, and metabolic intervention are most impactful when started in the 40s and 50s. RFC Longevity treats women across the full reproductive arc — fertility through post-menopause — because aging is a continuum, not a stage.

Advanced biomarker testing,built for women.

80+ biomarkers across hormonal, metabolic, cardiovascular, and reproductive health — analyzed and reviewed by Dr. Zaher Merhi, MD.

Explore the panel

The Full Panel

Where conventional medicinestops looking, we begin.

Eight body systems. Forty-plus markers. Each one connected to a clinical pattern — and a therapy we can apply.

System 01 / 08
ApoB
Apolipoprotein B-100
Apolipoprotein, ~4536 amino acids
Counts atherogenic particles directly — beats LDL cholesterol as a cardiovascular risk predictor.
Fasting glucose
C₆H₁₂O₆
Baseline blood sugar after overnight fast
Fasting insulin
Peptide
Rises years before glucose elevates — early metabolic warning
HbA1c
Glycated Hb
3-month average blood glucose
HOMA-IR
Calculated
Insulin resistance indicator from glucose + insulin
Total cholesterol
C₂₇H₄₆O
Combined cholesterol fractions
LDL-C
Lipoprotein
Low-density cholesterol carrier
HDL-C
Lipoprotein
High-density cholesterol carrier
Triglycerides
C₅₅H₁₀₀O₆
Stored fat circulating in blood
Lipoprotein(a)
Lp(a)
Genetic cardiovascular risk factor — one-time test
Non-HDL cholesterol
Calculated
All atherogenic cholesterol combined
System 02 / 08
AMH
Anti-Müllerian Hormone
Glycoprotein
The ovarian clock — measures remaining egg pool decades before menopause becomes clinical.
Estradiol (E2)
C₁₈H₂₄O₂
Primary estrogen — bone, brain, vaginal tissue, cardiovascular
Testosterone (total + free)
C₁₉H₂₈O₂
Androgen — libido, muscle, mood, cognition
SHBG
Glycoprotein
Sex hormone binding globulin — controls bioavailable testosterone
TSH
Glycoprotein
Pituitary signal to thyroid — most clinics stop here, we don't
Free T4
C₁₅H₁₁I₄NO₄
Thyroid precursor hormone
Free T3
C₁₅H₁₂I₃NO₄
Active thyroid hormone — what your cells use
IGF-1
Polypeptide
Insulin-like growth factor — proxy for growth hormone axis
Morning cortisol
C₂₁H₃₀O₅
Stress hormone — peak should be sharp at 7-8 AM
DHEA-S
C₁₉H₂₈O₅S
Anabolic adrenal hormone — opposes cortisol, declines with age
System 03 / 08
GGT
Gamma-glutamyltransferase
Liver enzyme
One of the strongest mortality predictors in medicine — and almost no clinic mentions it.
ALT
Enzyme
Alanine transaminase — primary liver injury marker
AST
Enzyme
Aspartate transaminase — liver and muscle injury
ALP
Enzyme
Alkaline phosphatase — liver and bone activity
Bilirubin
C₃₃H₃₆N₄O₆
Heme breakdown product — liver clearance marker
Albumin
Protein
Liver synthesis function
Creatinine
C₄H₇N₃O
Kidney filtration marker
eGFR
Calculated
Estimated glomerular filtration rate
BUN
Urea
Blood urea nitrogen — kidney function
Cystatin-C
Inhibitor
More sensitive kidney function marker than creatinine
System 04 / 08
hs-CRP
High-sensitivity C-reactive protein
Pentameric protein
The most-validated marker of chronic systemic inflammation in longevity medicine.
ESR
Sed. rate
Non-specific inflammation marker
Ferritin
Iron protein
Iron status AND acute-phase inflammation marker
CBC with differential
Cell counts
White blood cell subtypes reveal immune patterns
IL-6 (optional)
Cytokine
Master inflammatory signal driving CRP production
TNF-α (optional)
Cytokine
Tumor necrosis factor — chronic inflammation driver
System 05 / 08
Vitamin D (25-OH)
25-hydroxyvitamin D₃ (calcidiol)
C₂₇H₄₄O₂
A secosteroid hormone — not a vitamin. Affects bone, immunity, mood, and reproductive function.
Vitamin B12
C₆₃H₈₈CoN₁₄O₁₄P
Methylation, neurological function, energy metabolism
Folate
C₁₉H₁₉N₇O₆
DNA synthesis, methylation, fertility
Magnesium
Mg²⁺
Cofactor for 300+ enzymatic reactions
Zinc
Zn²⁺
Immune function, hormone production, fertility
Omega-3 / Omega-6 ratio
Fatty acids
Fatty acid balance — anti vs pro-inflammatory
System 07 / 08
Homocysteine
Homocysteine (sulfur-containing amino acid)
C₄H₉NO₂S
A sulfur amino acid that signals methylation dysfunction and cardiovascular risk.
Uric acid
C₅H₄N₄O₃
Purine metabolism, oxidative stress, cardiovascular risk
Oxidized LDL
Mod. LDL
Direct measure of oxidative damage to lipoproteins
GGT
Enzyme
Cross-listed — strong oxidative stress and mortality predictor
System 08 / 08
Lactobacillus crispatus
Lactobacillus crispatus (dominant healthy reproductive microbiome bacterium)
Gram-positive rod
The dominant healthy bacterium of the female reproductive tract — its absence drives chronic infection and infertility.
EMMA
Microbiome panel
Measures Lactobacillus dominance and bacterial composition
ALICE
Pathogen panel
Detects specific bacteria causing chronic endometritis
Vaginal microbiome panel
Bact. + fungal
Identifies pH, dominant species, dysbiosis, and infections

System 01 / 08

ApoB

Apolipoprotein B-100

Apolipoprotein, ~4536 amino acids

Counts atherogenic particles directly — beats LDL cholesterol as a cardiovascular risk predictor.

Fasting glucose
C₆H₁₂O₆
Baseline blood sugar after overnight fast
Fasting insulin
Peptide
Rises years before glucose elevates — early metabolic warning
HbA1c
Glycated Hb
3-month average blood glucose
HOMA-IR
Calculated
Insulin resistance indicator from glucose + insulin
Total cholesterol
C₂₇H₄₆O
Combined cholesterol fractions
LDL-C
Lipoprotein
Low-density cholesterol carrier
HDL-C
Lipoprotein
High-density cholesterol carrier
Triglycerides
C₅₅H₁₀₀O₆
Stored fat circulating in blood
Lipoprotein(a)
Lp(a)
Genetic cardiovascular risk factor — one-time test
Non-HDL cholesterol
Calculated
All atherogenic cholesterol combined

The next step

Testing without intervention
is just expensive curiosity.

Every biomarker we measure connects to a therapy we can apply. See how RFC translates findings into protocols built specifically for female biology.

Explore therapies Apply for RFC Longevity

Advanced biomarker testing,built for women.

Where conventional medicinestops looking, we begin.

ApoB

Fasting glucose

Fasting insulin

HbA1c

HOMA-IR

Total cholesterol

LDL-C

HDL-C

Triglycerides

Lipoprotein(a)

Non-HDL cholesterol

ApoB

Fasting glucose

Fasting insulin

HbA1c

HOMA-IR

Total cholesterol

LDL-C

HDL-C

Triglycerides

Lipoprotein(a)

Non-HDL cholesterol

Testing without interventionis just expensive curiosity.

Testing without intervention
is just expensive curiosity.