RFCLongevity
Reproductive & sexual longevity · by application

The reproductive longevity program,built inside your biology.

A physician-led program connecting fertility, hormones, sexual wellness, and metabolic aging — built by a reproductive endocrinologist, tracked across years.

Dr. Zaher Merhi, MD · 110+ publications · 5 locations NYC + CT
Your body, one system

Six body systems.
One integrated roadmap.

Most longevity programs test in silos. Ovaries here, thyroid there, metabolism somewhere else. We read them together — because your biology doesn't work in silos.

Tap a region
Translucent liquid glass female silhouette
The physician

Built by the doctor who pioneered
ovarian rejuvenation in the United States.

Dr. Zaher Merhi, board-certified reproductive endocrinologist and founder of RFC Longevity
Dr. Zaher Merhi, MD
Reproductive endocrinologist · Founder, RFC Longevity

For 25 years, Dr. Zaher Merhi has spent his career on a single question: how do we slow, measure, and reverse reproductive aging in women? He's a board-certified reproductive endocrinologist, a published researcher with 110+ peer-reviewed papers, and the first physician in the United States to develop ovarian platelet-rich plasma (PRP) protocols for diminished ovarian reserve.

Most longevity programs were designed by general internists, then retrofitted with hormone testing. RFC Longevity is the inverse — built from a reproductive medicine foundation outward. That's why we can read fertility, sexual wellness, hormones, and metabolic aging as one connected system, while everyone else reads them as four separate problems.

Aging in women isn't one clock. It's six. We measure all of them — and we act on what we find.

Dr. Zaher Merhi, MD
110+
peer-reviewed publications
25+
years in reproductive medicine
5
locations across NYC + CT
First
in the U.S. to perform ovarian PRP
Read Dr. Merhi's full bio →
As featured in:Forbes — twice.
How it works

Your roadmap,
in six phases.

Most longevity clinics hand you a panel of numbers and call it care. We don't. From application to annual tracking, every step is structured, physician-led, and personal — so you understand what's happening in your body and what we're doing about it.

Compare pathways.

Basic

$2,000
Physician-led consultation with Dr. Merhi
Comprehensive medical, metabolic, reproductive & sexual health evaluation
Core blood & hormone longevity testing
Personalized medication & supplement plan
Nutritional & lifestyle longevity guidance
Advanced aging & cellular biomarkers
Vaginal microbiome testing (when indicated)
EMMA / ALICE uterine testing (when indicated)
Microplastics blood testing
IV nutrient therapy
Long-term optimization & clinical support
Vaginal LLLT or ozone therapy
PRP therapy credit (ovarian / uterine / vaginal, when appropriate)
Results review & follow-ups1 follow-up

Comprehensive

$4,000
Physician-led consultation with Dr. Merhi
Comprehensive medical, metabolic, reproductive & sexual health evaluation
Core blood & hormone longevity testing
Personalized medication & supplement plan
Nutritional & lifestyle longevity guidance
Advanced aging & cellular biomarkers
Vaginal microbiome testing (when indicated)
EMMA / ALICE uterine testing (when indicated)
Microplastics blood testing
IV nutrient therapy1 session
Long-term optimization & clinical supportLimited
Vaginal LLLT or ozone therapy
PRP therapy credit (ovarian / uterine / vaginal, when appropriate)
Results review & follow-ups3 follow-ups

Deep Dive

$10,000
Physician-led consultation with Dr. Merhi
Comprehensive medical, metabolic, reproductive & sexual health evaluation
Core blood & hormone longevity testing
Personalized medication & supplement plan
Nutritional & lifestyle longevity guidance
Advanced aging & cellular biomarkers
Vaginal microbiome testing (when indicated)
EMMA / ALICE uterine testing (when indicated)
Microplastics blood testing
IV nutrient therapyUnlimited
Long-term optimization & clinical support
Vaginal LLLT or ozone therapy2 sessions
PRP therapy credit (ovarian / uterine / vaginal, when appropriate)1 credit
Results review & follow-upsPriority + 12-month monitoring
Clinical scenarios

What we evaluate. What we treat.

Three of the most common scenarios we see at RFC Longevity — and how a reproductive endocrinologist's evaluation differs from standard primary care.

Scenario 01

Fatigue, weight gain, and "normal" labs in women 35–50

Common presentation

Persistent fatigue despite adequate sleep. Weight gain — especially abdominal — that doesn't respond to diet or exercise. Cycle changes, mood shifts, low libido. Standard primary-care labs come back within reference range.

What we typically find
  • Suboptimal Free T3 with normal TSH
  • Elevated reverse T3 (often missed in standard panels)
  • Flattened cortisol diurnal rhythm
  • Declining DHEA-S and progesterone
  • Insulin resistance evident in HOMA-IR before glucose elevates
CORTISOL (NMOL/L)7AM12PM4PM8PM11PMHEALTHY RHYTHMPATIENT (FLATTENED)
Diurnal cortisol · Mortality risk ↑ when flattened
What we do about it

A targeted protocol combining individualized hormone optimization, adrenal-axis support, micronutrient correction, and metabolic intervention — calibrated to the specific pattern, not a one-size-fits-all script.

Why most clinics miss it

"Within range" is not the same as "optimal." Standard primary care looks at TSH alone and stops. We measure the conversion pathway, the reverse blockers, and the upstream stress axis driving the dysfunction.

Scenario 02

Fertility optimization in women 32–42 with "unremarkable" workups

Common presentation

Trying to conceive, considering egg freezing, or planning fertility ahead of timeline pressure. Initial OB workup returned "normal" results. Patient wants active optimization, not reassurance.

What we typically find
  • AMH lower than ideal for age, even within "normal" range
  • Suboptimal follicular-phase estradiol and luteal-phase progesterone
  • Vitamin D, B12, or iron deficits affecting egg quality
  • Undiagnosed chronic endometritis (present in up to 19.5% of women with infertility, per 2024 meta-analysis)
  • Thyroid antibodies elevated despite normal TSH
AMH (NG/ML)2832384245AGE-NORMAL RANGEPATIENT
AMH by age · The optimizable margin between fine and ideal
What we do about it

Comprehensive reproductive optimization — micronutrient correction, mitochondrial support for egg quality, microbiome restoration where indicated, and where appropriate, regenerative protocols including ovarian PRP (pioneered at RFC).

Why most clinics miss it

Standard fertility workups are designed to identify problems severe enough to require IVF. They don't identify the optimizable margin between "fine" and "ideal." That margin is where the next 5 years of fertility live.

Scenario 03

Longevity testing for women who've outgrown general wellness

Common presentation

Health-literate women who've already done basic longevity testing — VO2 max, lipid panel, fasting insulin — and want deeper evaluation specifically calibrated to female biology and reproductive health.

What we typically find
  • ApoB and Lp(a) elevations missed by standard cholesterol panels
  • Microplastic accumulation in blood (emerging biomarker, available through specialized testing)
  • Microbiome disruption affecting hormonal metabolism
  • Estrogen detoxification pathway inefficiencies
  • Cellular aging markers misaligned with chronological age
MICROPLASTIC PARTICLES (/ML BLOOD)POPULATION AVG~15/ML015304560POPULATION DISTRIBUTIONPATIENT
Microplastic blood test · Emerging biomarker · Few clinics measure it
What we do about it

Advanced biomarker panel with reproductive endocrinology overlay, regenerative therapy protocols (PRP, ozone, IV nutrient therapy), and longitudinal monitoring designed for biological-age tracking, not annual checkups.

Why most clinics miss it

General longevity programs were built around male physiology and bolted on hormone testing as an afterthought. Female longevity follows a different clock — and requires medicine designed for it.

Common questions

Questions,
answered honestly.

The questions women actually ask before applying — about sexual wellness, the program structure, and how RFC Longevity differs from everything else.

Still have questions? The 30-minute discovery call answers everything else.

Low libido. Vaginal dryness and atrophy. Painful intercourse (dyspareunia). Loss of arousal. Difficulty with orgasm. Post-childbirth tissue changes. Post-menopausal sexual function decline. Reduced sensation. We address these through hormone optimization, regenerative therapies (Vaginal PRP, low-level laser therapy, ozone), microbiome restoration, and individualized clinical protocols. Sexual wellness isn't a bolt-on aesthetic service at RFC — it's measured and treated as a core longevity outcome. Dr. Merhi is one of the few reproductive endocrinologists in the U.S. integrating these therapies into a longevity framework.

Because sexual function is one of the most reliable indicators of how a woman's body is aging — and most longevity programs ignore it entirely. Libido depends on testosterone, estradiol, DHEA, and dopamine signaling. Vaginal tissue health reflects estrogen status, microbiome integrity, and inflammatory burden. Orgasmic function tracks pelvic blood flow and nerve health. We measure all of it because it tells us things blood pressure and ApoB don't. Sexual wellness isn't separate from longevity — it's longevity, in one of its most measurable forms.

Vaginal PRP uses a small sample of your own blood, processed to concentrate the growth factors and platelets, then injected into vaginal and surrounding tissue to stimulate regeneration. Because the material is your own blood, there's no risk of allergic reaction or rejection. The procedure takes under an hour, is performed in-office with local anesthetic, and most patients return to normal activity within 24–48 hours. It's part of the same regenerative platform RFC pioneered for ovarian rejuvenation.

No. RFC Longevity is a private, application-based program. Insurance does not cover preventive longevity care, advanced biomarker panels, or regenerative therapies in the United States. Some specific lab work and prescriptions ordered through the program may be reimbursable through your existing insurance — we provide superbills you can submit. But the program fees themselves are paid out of pocket, like any concierge medical program.

Most patients travel in for the testing visit and physician review, then continue on telehealth from anywhere in the U.S. We have five physical locations across Manhattan, Brooklyn, Westchester, Long Island, and Westport, CT — plus an option for in-person treatment retreats in the Bahamas for select patients in our Deep Dive pathway. Roughly half of our patients fly in once a year for testing and stay local; the other half live in the tri-state area.

Function Health is an algorithm-driven biomarker dashboard with optional generalist physician review. RFC Longevity is a physician-built clinical program where Dr. Merhi — a reproductive endocrinologist with 110+ peer-reviewed publications — personally reviews every panel and builds every protocol. Function Health is a self-serve tool. RFC Longevity is medicine. The other major difference: Function Health doesn't address sexual wellness, regenerative therapies, or reproductive health at any meaningful clinical level. We do.

Most concierge longevity programs were designed by general internists who added hormone testing as an afterthought. RFC Longevity is the inverse — built outward from a reproductive endocrinology foundation. That means we read hormones, fertility markers, sexual function, microbiome, and metabolic signals as one connected system. Other programs price at $20K–$100K per year. We're priced from $2K to $10K. The depth, especially around female-specific biology, is what's different.

Not currently. RFC Longevity is designed specifically around female reproductive, sexual, and hormonal biology — and the medicine, biomarkers, and therapies are calibrated for women. The longevity industry already has many programs built around male physiology; we built this one for the half of the population that's been treated as a footnote.

No. After your testing and physician review, Dr. Merhi builds a written, individualized plan that connects every finding in your panel to a specific therapy or intervention. That can include prescription hormone optimization, IV nutrient protocols, regenerative procedures (where appropriate), microbiome restoration, targeted supplementation, and lifestyle adjustments. The protocol is calibrated to your biomarker pattern. There is no template. Two women in the same age bracket with the same symptoms will often leave with different protocols because their underlying drivers are different.

It's not too late. Perimenopause and menopause are exactly the windows where most women in the U.S. fall through the cracks of standard care — and where the right interventions create the most measurable change. Hormone optimization, sexual wellness restoration (including Vaginal PRP and LLLT for vaginal tissue regeneration), bone health monitoring, and metabolic intervention are most impactful when started in the 40s and 50s. RFC Longevity treats women across the full reproductive arc — fertility through post-menopause — because aging is a continuum, not a stage.

The next step

Your biology is moving.
So should you.

RFC Longevity is application-only. We review every application personally, and we’ll be in touch within two business days to schedule your discovery call.

Apply for RFC Longevity
5 Locations · Tri-State + Bahamas Retreat
  • Manhattan
  • Brooklyn
  • Westchester
  • Long Island
  • Westport, CT
  • Bahamas